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Compound profiles

What is AOD-9604?

⚡ Short answer

AOD-9604 is a synthetic 16-amino-acid peptide based on the end section of human growth hormone (amino acids 177 to 191), with an extra tyrosine added at the start. It is not an approved medicine, and the World Anti-Doping Agency prohibits it.

Educational onlyUpdated 22 Oct 20264 sources
Compound profiles

Where it comes from

Human growth hormone is a protein of 191 amino acids. AOD-9604 copies its last 15 amino acids and adds a tyrosine (Y) at the front, giving 16 in total.

It was developed in Australia as a drug candidate. Its clinical programme did not lead to an approved medicine, and it is not licensed anywhere.

Compound profiles

A small loop in the chain

The sequence contains two cysteines (C). In the finished peptide they are joined by a disulfide bridge, which closes part of the chain into a loop. That matters for testing:

Mass spectrometry should match about 1,815.1 g/mol.
A version where the bridge has not formed weighs 2 g/mol more, so a careful lab report can tell the two apart.
HPLC purity should be reported for the same batch number that is on the vial.
Compound profiles

Regulatory and sporting status

AOD-9604 is not an approved medicine in the UK, the EU or the US. In the UK, a product presented or sold for use in people is treated as a medicine, which needs a licence from the MHRA.

The FDA lists AOD-9604 among bulk substances that may present significant safety risks in compounding, citing possible immune reactions and difficulty characterising peptide impurities.

The WADA Prohibited List names AOD-9604 as an example of a prohibited growth hormone fragment, banned in and out of competition.

Educational information only

Educational information only. Nothing here is medical advice, dosing guidance or a recommendation to use any substance. Research peptides are not approved medicines and are not for human or animal consumption. Speak to a qualified professional and follow the law where you are.

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