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Compound profiles

What is GHK-Cu?

⚡ Short answer

GHK-Cu is the tripeptide glycyl-histidyl-lysine (GHK) bound to a copper ion. GHK was first isolated from human blood plasma in 1973, and the copper complex is used in cosmetics as "copper tripeptide-1".

Educational onlyUpdated 21 Oct 20261 source
Compound profiles

A tiny peptide holding a copper ion

GHK is one of the smallest peptides there is: just glycine, histidine and lysine. It binds copper tightly, and the copper complex is what is sold as GHK-Cu. The copper gives the powder and its solutions their blue colour.

GHK was first isolated from human plasma by the researcher Loren Pickart in 1973.

Compound profiles

Cosmetic versus research grade

In skincare, GHK-Cu appears in ingredient lists as "copper tripeptide-1" and is regulated as a cosmetic ingredient, not a medicine.

Research-grade GHK-Cu is sold separately, for laboratory use only. As with any research material, the certificate of analysis should confirm identity by mass and purity by HPLC for the batch you have.

Educational information only

Educational information only. Nothing here is medical advice, dosing guidance or a recommendation to use any substance. Research peptides are not approved medicines and are not for human or animal consumption. Speak to a qualified professional and follow the law where you are.

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