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Compound profiles

What is TB-500?

⚡ Short answer

TB-500 is a market name for a synthetic peptide based on thymosin beta-4, a natural 43-amino-acid protein. What is sold under the name varies, so only a mass test shows which version a vial contains.

Educational onlyUpdated 21 Oct 20262 sources
Compound profiles

One name, several products

Thymosin beta-4 is a 43-amino-acid protein found naturally in the body. "TB-500" is not a scientific name; it is a label used in the market.

PubChem's TB-500 entry is the short fragment LKKTETQ, 7 amino acids at 889.0 g/mol. Some sellers supply an acetylated version of that fragment, and some supply the full-length protein at about 4,963 g/mol, all under the same name.

Compound profiles

How to tell them apart

The mass is the giveaway. A mass spectrometry report on the certificate of analysis should show a mass that matches the product named on the label. A 7-amino-acid fragment and the full 43-amino-acid protein differ by more than 4,000 g/mol, so the two cannot be confused on a genuine report.

Compound profiles

Regulatory and sporting status

TB-500 is not an approved medicine in the UK, the EU or the US.

The World Anti-Doping Agency prohibits thymosin beta-4 and its derivatives, naming TB-500, under growth factors.

Educational information only

Educational information only. Nothing here is medical advice, dosing guidance or a recommendation to use any substance. Research peptides are not approved medicines and are not for human or animal consumption. Speak to a qualified professional and follow the law where you are.

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